Kombucha is an increasingly consumed product sometimes considered as a nutraceutical. This product originated in Asia is a non-or-low-alcoholic functional beverage, slightly acidic andcarbonated. It is obtained by the fermentation of sweetened tea by a symbiotic culture of bacteria and yeast, called SCOBY. These microorganisms as well as the chemical composiition isvarying. However the main genus always present in komucha are for yeasts Brettanomyces and Zygosaccharomyces and for acetic acid bacteria Komagateibacter. In some studies lactic acidbacteria have also been reported. Some of these microrganisms have probiotic properties and can survive in the beverage once in bottle.The chemical composiiton depends of course on the fermentation conditions and on the substrate. The main microbial metabolites are organic acids (acetic and glucuronic), ethanol, Band C vitamins. Many phenolic coumponds originated from tea but modified by the fermentation are always present at low concentration. All these coumpounds contributes to the numerousbiological activities associated with Kombucha such as anti-oxydant, anti-inflammatory, anticholesterol,.... . Some of them have been demonstrated in vivo.Non-typical substrates (fruits, vegetables, plants, herbs, dairy, and by-products) are being inoculated with the kombucha consortium in an attempt to develop new products with attractive properties.We will specifically present the resuls obtained wih grape pomace as substrate leading to extracts with anti-oxydant, antidiabetic and anti-inflammatory activites demonstrated in vitro.
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