La producción de interferón gamma (IFN-y) se asocia a una menor concentración plasmática de proteína asociada a la gestación-1 y -2 (PAG-1 y PAG-2) en vacas lecheras gestantes crónicamente infectadas por neospora caninum
-
B. Serrano Perez [1] ; I. García Isperto [1] ; C. Nogareda [1] ; S. Almería [2] ; F. López Gatius [1]
-
[1] Universitat de Lleida
Universitat de Lleida
Lérida, España
-
[2] UAB-IRTA
-
- Localización: XV Jornadas sobre Producción Animal: 14 y 15 de mayo de 2013, Zaragoza / Jorge Hugo Calvo Lacosta (aut.), Isabel Casasús Pueyo (aut.), Margalida Joy Torrens (aut.), Javier Álvarez Rodríguez (aut.), Luis Varona Aguado (aut.), Begoña Panea Doblado (aut.), Carlos Calvete Margolles (aut.), Joaquim Barcells Teres (aut.), Vol. 1, 2013, ISBN 978-84-695-7684-7, págs. 323-325
- Idioma: español
- Títulos paralelos:
- Gamma interferon production is related to lower pregnancy associated glycoprotein-1 and -2 (PAG-1 and PAG-2) concentrations in non-aborting chronically neospora caninum-infected dairy cows
- Enlaces
-
Resumen
The objective of this work was to study the interaction between gamma interferon (IFN-y) production and plasma pregnancy-associated glycoprotein-1 (PAG-1) and -2 (PAG-2) concentrations throughout pregnancy in non-aborting chronically Neospora caninum-infected cows. Gamma interferon was detected at some point along the pregnancy in 9 (21%) of the 43 Neospora-seropositive cows. General lineal models (GLM) repeated measures ANOVA revealed significant effect of IFN-y production on plasma PAG-1 and PAG-2. IFN-y production was related to lower PAG-1 concentrations throughout gestation (P<0.05), respect to cows not producing IFN-y. Moreover, cows not producing IFN- showed significantly increased PAG-1 and PAG-2 concentrations at Day 120 of gestation (P<0.01 and P<0.05, respectively), respect to cows producing IFN-y. These results indicate that IFN- production has an effect on placental PAG secretion in non aborting Neospora-infected cows.
