Expresión de los receptores tipo Toll en el epitelio ruminal de cabras desde el nacimiento hasta los 28 días de edad en dos sistemas de alimentación
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L. Abecia [1] ; E. Jiménez [1] ; G. Martinez Fernandez [1] ; E. Ramos Morales [1] ; A.I. Martín García [1] ; D.R. Yañez Ruiz [1]
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[1] CSIC
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- Localización: XVI Jornadas sobre Producción Animal: 19 y 20 de mayo de 2015, Zaragoza / Javier Álvarez Rodríguez (aut.), Begoña Panea Doblado (aut.), Jorge Hugo Calvo Lacosta (aut.), Mireia Blanco Alibés (aut.), José Alfonso Abecia Martínez (aut.), Daniel Villalba Mata (aut.), María Ángeles Latorre Górriz (aut.), Vol. 1, 2015, ISBN 978-84-606-7969-1, págs. 233-235
- Idioma: español
- Títulos paralelos:
- Gene expression of Toll-like receptors in the rumen of goat kids from birth to 28 days old in two feeding managements
- Enlaces
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Resumen
The aim of this work was to evaluate the effect of feeding management and subsequent microbial colonization pattern during the first month of life on the expression of toll-like receptors (TLRs) in the rumen epithelium. Twenty four pregnant goats carrying two fetuses were selected. At birth one kid was taken immediately away from the doe and fed milk replacer (ART) while the other remained with the mother (NAT). Groups of four kids (from ART and NAT experimental groups) were slaughtered at 3, 5, 7, 14, 21 and 28 days of life. On the sampling day, epithelial tissue was collected from rumen wall. Expression TLRs 2, 8 and 10 were lower at day 3 and 5 compared to the other sampling days. Only TLR5 showed different level of expression according to the feeding system, presenting higher mRNA abundance in ART group. These results suggest that the expression of TLRs is related to the rumen development process and bacterial biomass colonization and co-evolve with the commensal microbiota that colonizes after birth. We hypothesize that there might be a stronger link between TLRs activity and the epimural microbial community, which is currently being investigated.
