Trends in pharmacological sciences

• 

  Año 2003, Vol. 24, Número 2 (February)

  • Research Focus

    • Interfering with leukocyte rolling ¿ a promising therapeutic approach in inflammatory skin disorders?

      Michael P. Schön, Wolf-H. Boehncke

      • Resumen

      págs. 49-51

      

    • Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor family

      Maria P. Abbracchio, Eric A. Barnard, Jean-Marie Boeynaems

      • Resumen

      págs. 52-54

      

    • Using genome-wide mapping in the mouse to identify genes that influence drug response

      James W. Watters, Howard McLeod

      • Resumen

      págs. 55-57

      

    • Crystallization of the human glucocorticoid receptor ligand binding domain: a step towards selective glucocorticoids

      Brian M. Necela, John A. Cidlowski

      • Resumen

      págs. 58-60

      

  • Letters

    • Do unpredictable toxic side-effects of drugs reflect their promiscuous binding energies?

      Alan Wiseman

      págs. 61-62

      

    • Pharmacological effects of garlic extract

      Ruomei Qi, Zhengang Wang

      págs. 62-63

      

    • Empirical models and Hill coefficients

      Jesús Giraldo

      págs. 63-65

      

  • Opinion

    • Too much of a good thing: adenosine overload in adenosine-deaminase-deficient mice

      Michael R. Blackburn

      • Resumen

      págs. 66-70

      

    • Acquired somatic mutations in the molecular pathogenesis of COPD

      Gary P. Anderson, Steven Bozinovski

      • Resumen

      págs. 71-76

      

    • Obesity ¿ a chronic health problem in cloned mice?

      Akio Inui

      • Resumen

      págs. 77-80

      

    • Agonist induction and conformational selection during activation of a G-protein-coupled receptor

      Patrick Vanderheyden, László Hunyady, Georges Vauquelin

      • Resumen

      págs. 81-86

      

  • review

    • Principles: Extending the utility of [35S]GTPS binding assays

      Graeme Milligan

      • Resumen

      págs. 87-90

      

    • Endothelial nitric oxide synthase: the Cinderella of inflammation?

      Giuseppe Cirino, Stefano Fiorucci, William C. Sessa

      • Resumen

      págs. 91-95

      

    • Cyclooxygenase 2: a molecular target for cancer prevention and treatment

      Jaime Dannenberg, Kotha Subbaramaiah

      • Resumen

      págs. 96-102