Resumen de Insights into incipient oral squamous cell carcinoma: a comprehensive south-american study
Cristina Saldivia-Siracusa, Anna Luiza Damaceno Araújo, Lady Paola Aristizábal Arboleda, Thamiris Abrantes, Mariana-Bitu-Ramos Pinto, Nathalia Mendonça, Karina Cordero Torres, Gerardo Guilligan, Eduardo Piemonte, René Luis Panico, Fabio Abreu Alves, Mariana Villarroel Dorrego, Mário José Romañach, Aline Corrêa-Abrahão, Wilfredo González-Arriagada, Keith Hunter, Ana-Carolina-Prado Ribeiro, Márcio Ajudarte Lopes, Pablo Agustín Vargas, Alan Roger Santos Silva
To describe demographic and clinicopathological aspects of a South-American cohort of incipient oral squamous cell carcinoma patients.
A cross-sectional, observational study was performed to assess demographic and clinicopathological characteristics of incipient oral squamous cell carcinoma patients from 6 South-American institutions.
One hundred and seven patients within the histopathological spectrum of incipient oral squamous cell carcinoma (in-situ and microinvasive) were included. Fifty-eight (54.2%) patients were men with a mean age of 60.69 years. Forty-nine (45.8%) and thirty-nine (36.5%) patients had history of tobacco and alcohol use, respectively. Clinically, most of the lesions were plaques (82.2%), ≥ 2 cm in extension (72%), affecting the lateral border of the tongue (55.1%), and soft palate (12.1%) with a mixed (white and red) appearance. Eighty-two (76.7%) lesions were predominantly white and 25 (23.3%) predominantly red.
To the best of our knowledge, this is the largest cohort of incipient oral squamous cell carcinoma patients, which raises awareness of clinicians’ inspection acuteness by demonstrating the most frequent clinical aspects of this disease, potentially improving oral cancer secondary prevention strategies.
