Resumen de Bias induced during the estimation of quality-adjusted life-years
Alexandra Welsh, Deborah A. Costain, Andrew C. Titman
Quality-adjusted life-years (QALYs) are a summary measure used to evaluate the e ectiveness of medical treatments in terms of both quality and length of life. One method used to estimate QALYs is the area under the timeutility curve (AUC). However, this approach may induce bias, due to its inability to capture the dependency between the quality of life measures and the survival time. A simulation study is conducted to assess the bias induced when estimating QALYs using the AUC method, using data including censored individuals and missing responses.
