Resumen de Reduction of 5-nitrofuran compounds catalyzed by a rhodium complex immobilized on poly(4-vinylpyridine): A relationship with antibacterial activity

M. E. Farkas, E. Rodriguez, C Longo, Melina Monasterios, M. C. Ortega, A. B. Rivas, A. J. Pardey, Rosa López, S. A Moya

• This paper describes the catalytic activation studies of the reduction of some 2-substituted-5-nitrofuran compounds by [Rh(COD)(2-picoline)2](PF6) (COD = 1,5-cyclooctadiene) anchored on poly(4-vinylpyridine) in contact with 80% aqueous 2-ethoxyethanol at 100 º C under carbon monoxide atmosphere. The effect of varying the nature of the 2-substituents of the furan ring was evaluated. The importance of the present catalysis studies can be emphasized, because the potential activity against bacteria of the 2-substituted-5-nitrofuran compounds could be monitored by determining the facility of catalytic reduction of the nitro group