Reduction of 5-nitrofuran compounds catalyzed by a rhodium complex immobilized on poly(4-vinylpyridine): A relationship with antibacterial activity

• M. E. FARKAS ^[3] ; E RODRÍGUEZ ^[3] ; C LONGO ^[1] ; M MONASTERIOS ^[1] ; M. C. ORTEGA ^[1] ; A. B. RIVAS ^[1] ; A. J. PARDEY ^[1] ; R LÓPEZ ^[2] ; S.A. MOYA ^[2]
  1. [1] Universidad Central de Venezuela

     Universidad Central de Venezuela

     Venezuela

     
  2. [2] Universidad de Santiago de Chile

     Universidad de Santiago de Chile

     Santiago, Chile

     
  3. [3] Universidad Simón Bolívar Departamento de Química

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• Localización: Journal of the Chilean Chemical Society (Boletín de la Sociedad Chilena de Química), ISSN-e 0717-6309, ISSN 0366-1644, Vol. 51, Nº. 1, 2006, págs. 829-835
• Idioma: inglés
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  • This paper describes the catalytic activation studies of the reduction of some 2-substituted-5-nitrofuran compounds by [Rh(COD)(2-picoline)2](PF6) (COD = 1,5-cyclooctadiene) anchored on poly(4-vinylpyridine) in contact with 80% aqueous 2-ethoxyethanol at 100 º C under carbon monoxide atmosphere. The effect of varying the nature of the 2-substituents of the furan ring was evaluated. The importance of the present catalysis studies can be emphasized, because the potential activity against bacteria of the 2-substituted-5-nitrofuran compounds could be monitored by determining the facility of catalytic reduction of the nitro group