Resumen de Synthesis and characterization of bis- and tos-(4-carboxybenzoyl)-alkaneamines
L Guarda, N Parra, M. S Chavez, J Belmar, C. A Jimenez, J. Pasan, C Ruiz-perez
A practical and efficient protocol to obtain bis- and tris-(4-carboxybenzoyl)alkaneamines based on monoprotected 1,4-benzenedicarboxylic acid is reported here. N-(4-methoxycarbonylbenzoyloxy)succinimide was treated with aliphatic diamines and triamines to form aliphatic hydrocarbon-linked bis- and tris-amides 4a-4e. The yields ranged from good to very good and showed that choosing the right acylating agent is a key point in this synthesis. All the compounds were characterized by elemental analysis, FTIR, and ¹H NMR.
