Synthesis and characterization of bis- and tos-(4-carboxybenzoyl)-alkaneamines

• L GUARDA ^[1] ; N PARRA ^[1] ; M. S CHAVEZ ^[1] ; J BELMAR ^[1] ; C. A JIMENEZ ^[1] ; J PASAN ^[2] ; C RUIZ-PEREZ ^[2]
  1. [1] Universidad de Concepción

     Universidad de Concepción

     Comuna de Concepción, Chile

     
  2. [2] Universidad de La Laguna

     Universidad de La Laguna

     San Cristóbal de La Laguna, España

     
• Localización: Journal of the Chilean Chemical Society (Boletín de la Sociedad Chilena de Química), ISSN-e 0717-6309, ISSN 0366-1644, Vol. 57, Nº. 3, 2012, págs. 1305-1308
• Idioma: inglés
• Enlaces
  • Texto completo
• Resumen

  • A practical and efficient protocol to obtain bis- and tris-(4-carboxybenzoyl)alkaneamines based on monoprotected 1,4-benzenedicarboxylic acid is reported here. N-(4-methoxycarbonylbenzoyloxy)succinimide was treated with aliphatic diamines and triamines to form aliphatic hydrocarbon-linked bis- and tris-amides 4a-4e. The yields ranged from good to very good and showed that choosing the right acylating agent is a key point in this synthesis. All the compounds were characterized by elemental analysis, FTIR, and ¹H NMR.