Resumen de Comparative studies of lewis acidity of alkyl-tin chlorides in multicomponent biginelli condensation using grindstone chemistry technique
Harshita Sachdeva, Rekha Saroj, Sarita Khaturia, Har Lal Singh
A simple and efficient procedure for the one pot Biginelli Condensation Reaction of aldehydes, â-ketoester and urea employing SnCl4.5H2O /mono/di/tri-butyl- tin chloride as a novel catalyst is described. Compared to classical Biginelli reaction conditions, the present method has the advantages of good yields, short reaction times and experimental simplicity. Further, comparative efficiency of alkyl- tin chlorides in multicomponent Biginelli Condensation Reaction is also studied under solvent free conditions.
