Comparative studies of lewis acidity of alkyl-tin chlorides in multicomponent biginelli condensation using grindstone chemistry technique

• HARSHITA SACHDEVA ^[1] ; REKHA SAROJ ^[1] ; SARITA KHATURIA ^[1] ; HAR LAL SINGH ^[1]
  1. [1] Mody Institute of Technology and Science Faculty of Engineering and Technology Department of Chemistry
• Localización: Journal of the Chilean Chemical Society (Boletín de la Sociedad Chilena de Química), ISSN-e 0717-6309, ISSN 0366-1644, Vol. 57, Nº. 1, 2012, págs. 1012-1016
• Idioma: inglés
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• Resumen

  • A simple and efficient procedure for the one pot Biginelli Condensation Reaction of aldehydes, â-ketoester and urea employing SnCl4.5H2O /mono/di/tri-butyl- tin chloride as a novel catalyst is described. Compared to classical Biginelli reaction conditions, the present method has the advantages of good yields, short reaction times and experimental simplicity. Further, comparative efficiency of alkyl- tin chlorides in multicomponent Biginelli Condensation Reaction is also studied under solvent free conditions.