Resumen de Synthesis and crystal structure analysis of a new chalcone derivative of apocynin
M. Zárraga, F. Rivera, P. Arroyo, A. Miranda, Ricardo Baggio, L. Álvarez, Y. Moreno
In the present report we present the synthesis and structural analysis of a chalcone derivative of Apocynin, 1-(4-hydroxy-3-methoxyphenyl)-3-(4-nitrophenyl)-2-propenone. The most characteristic feature of its molecular structure is its near-planarity, allowing molecules to be stacked in columns, at graphite intermolecular distances to each other and connected by a large variety of weak intermolecular interactions. The molecule presents structural analogies to related ones with significant pharmacological properties (e.g., Apocynin).
