In rabbits, artificial insemination requires an effective control of ovulation, The most frequent method used for ovulation induction in rabbits artificially inseminated is the intramuscular administration of GnRH, but there are clear breeding advantages using the GnRH analogue on seminal dose. In this respect, several authors reported the possibility of ovulation induction after supplementation of semen extender with a GnRH synthetic analogue. Therefore, the concentration of GnRH analogue needed when it is included in the extender is much higher than that used intramuscularly. On the other hand, seminal plasma from several species has an important aminopeptidase activity, and this proteolitic activity could alter the effective concentration of GnRH analogue available to be absorbed via vaginal mucosa. The aim of this study was to evaluate de effect of the genetic line on the alanine aminopeptidase activity in the seminal plasma of male rabbits. Results showed that A line, selected for maternal characteristics, showed a significantly lower aminopeptidase activity than R line, selected for growth rate from weaning to slaughter. This result suggests that the genetic line of the male could determine the concentration of GnRH analogues needed in supplemented extenders to obtain similar reproductive performance than that obtained after intramuscular administration.
© 2001-2025 Fundación Dialnet · Todos los derechos reservados