Resumen de SEOM-GEMCAD-TTD clinical guidelines for localized rectal cancer (2021)

Jaume Capdevila Castillon, M. A. Gómez España, Mónica Maria Guillot Morales, David Páez López-Bravo, Carles Pericay Pijaume, María José Safont, Noelia Tarazona Llavero, Ruth Vera García, Joana Vidal, Javier Sastre Valera

• The management of localized rectal cancer requires a multidisciplinary approach to optimize outcomes, reduce morbidity and prevent under or overtreatments. While early stages may obtain benefit of local resections without any additional therapies, locally advanced rectal cancer becomes a challenge defining the better sequential strategy of surgery, radiotherapy and chemotherapy. The latest results of international phase III studies have positioned the total neoadjuvant therapy as a potential new standard of care in high risk rectal cancers, however, the best schedule is still not well defined.