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SEOM-GEMCAD-TTD clinical guidelines for localized rectal cancer (2021)

    1. [1] Hospital Universitario Reina Sofia

      Hospital Universitario Reina Sofia

      Cordoba, España

    2. [2] Hospital Universitario Son Espases

      Hospital Universitario Son Espases

      Palma de Mallorca, España

    3. [3] Hospital de la Santa Creu i Sant Pau

      Hospital de la Santa Creu i Sant Pau

      Barcelona, España

    4. [4] Hospital General Universitario de Valencia

      Hospital General Universitario de Valencia

      Valencia, España

    5. [5] Hospital Clínico San Carlos de Madrid

      Hospital Clínico San Carlos de Madrid

      Madrid, España

    6. [6] Department of Medical Oncology, Vall Hebron University Hospital, Vall Hebron Institute of Oncology (VHIO), Barcelona, Spain
    7. [7] Department of Medical Oncology, Hospital Universitari Mútua de Terrassa, Terrassa, Spain
    8. [8] Department of Medical Oncology, INCLIVA Biomedical Research Institute, University of Valencia, Valencia, Spain Instituto de Salud Carlos III, CIBERONC, Madrid, Spain
    9. [9] Department of Medical Oncology, Hospital Universitario de Navarra; Navarrabiomed, IDISNA, Pamplona, Spain
    10. [10] Department of Medical Oncology, Hospital del Mar-IMIM, CIBERONC, Barcelona, Spain
  • Localización: Clinical & translational oncology, ISSN 1699-048X, Vol. 24, Nº. 4 (April), 2022, págs. 646-657
  • Idioma: inglés
  • Enlaces
  • Resumen
    • The management of localized rectal cancer requires a multidisciplinary approach to optimize outcomes, reduce morbidity and prevent under or overtreatments. While early stages may obtain benefit of local resections without any additional therapies, locally advanced rectal cancer becomes a challenge defining the better sequential strategy of surgery, radiotherapy and chemotherapy. The latest results of international phase III studies have positioned the total neoadjuvant therapy as a potential new standard of care in high risk rectal cancers, however, the best schedule is still not well defined.


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