Association of celiac disease in patients with multiple sclerosis in Tuscany

• Barbara Piccini ^[1] ; Monica Ulivelli ^[2] ; Maria Pia Amato ^[3] ; Sabina Bartalini ^[4] ; Mario Falcini ^[5] ; Marta Giannini ^[3] ; Eliana Magnani ^[3] ; Luca Massacesi ^[3] ; Anna Maria Repice ^[3] ; Marina Vascotto ^[4] ; Salvatore Grosso ^[2]
  1. [1] Meyer Children's Hospital

     Meyer Children's Hospital

     Firenze, Italia

     
  2. [2] Università degli Studi di Siena

     Università degli Studi di Siena

     Siena, Italia

     
  3. [3] University of Florence

     University of Florence

     Firenze, Italia

     
  4. [4] University Hospital Santa Maria alle Scotte. Siena, Italy
  5. [5] Santo Stefano Hospital. Prato, Italy

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• Localización: Revista Española de Enfermedades Digestivas, ISSN-e 2340-4167, ISSN 1130-0108, Vol. 112, Nº. 6, 2020, págs. 474-476
• Idioma: inglés
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• Resumen

  • Background and study purpose: to describe the comorbidity of celiac disease among a large cohort of multiple sclerosis patients in Tuscany. Methods: the association of celiac disease among multiple sclerosis adult patients (n=2050) was retrospectively evaluated. Results: 13 patients were diagnosed with celiac disease, the female:male ratio was 3.3:1 and the median age at diagnosis was 34.2 years (SD 13). Seventy-seven per cent of subjects complained about gastrointestinal symptoms. IgA anti- transglutaminase was positive in 85 % of cases and there was 70 % of villous atrophy. Conclusions: the frequency of celiac disease among multiple sclerosis patients examined was lower than in the general population, 0.6 % vs 1 %)(p = 0.65).