Carbon-Based Fingerprint Powder as a One- Step Development and Matrix Application for High-Resolution Mass Spectrometry Imaging of Latent Fingerprints
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Paige Hinners [1] ; Young Jin Lee [1]
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[1] Iowa State University
Iowa State University
Township of Franklin, Estados Unidos
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- Localización: Journal of forensic sciences, ISSN-e 1556-4029, ISSN 0022-1198, Vol. 64, Nº. 4, 2019, págs. 1048-1056
- Idioma: inglés
- Texto completo no disponible (Saber más ...)
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Resumen
Carbon-based materials are often used as matrices for matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) and its imaging (MALDI-MSI). However, researchers have refrained from using carbon-based fingerprint powder (CFP) as a matrix dueto high background and contamination. In this work, the compatibility of CFP is reevaluated with MALDI-MSI using a high-resolution mass spectrometer (HRMS) and compared to traditional organic matrices. Relevant fingerprint compounds were easily distinguished from carbon cluster peaks when using HRMS. For fair comparison, half of a fingerprint was dusted with CFP while the other half was dusted with traditional organic matrices. All compounds studied had comparable, or higher, signal-to-noise (S/N) ratios when CFP was used as the matrix. Additionally, chemical image qualities closely followed the trend of S/N ratios. CFP proved to be an effective one-step development and matrix application technique for MALDI-MSI of latent fingerprints, when carbon cluster peaks are well separated by a HRMS.
