Fan Chen, Yi Ye, Bo Jin, Bo Yi, Qingtao Wei, Linchuan Liao
Paraquat poisoning usually results from suicide, occupational, or accidental exposure. Herein, we report a rare fatal case of homicidal paraquat poisoning. A 58-year-old man was poisoned by taking paraquat-mixed medicine and wearing paraquat-soaked underwear. In the absence of a history of paraquat exposure, the patient was misdiagnosed with pulmonary infection and scrotal dermatitis and died of respiratory failure 24 days after the initial exposure to paraquat. Ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was applied to detect and quantify paraquat in postmortem specimens. The concentration of paraquat in postmortem specimens from high to low is lung (0.49 ug/g), brain (0.32 ug/g), kidney (0.24 ug/g), liver (0.20ug/g), cardiac blood (0.11ug/mL), and stomach wall (
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