Homicidal Paraquat Poisoning

• Chen, Fan ^[1] ; Ye, Yi ; Jin, Bo ^[2] ; Yi, Bo ^[3] ; Wei, Qingtao ^[1] ; Liao, Linchuan
  1. [1] Department of Forensic Toxicological Analysis, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University.China
  2. [2] Department of Forensic Medicine, North Sichuan Medical College,China
  3. [3] Public Security Sub‐Bureau of Shunqing.China

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• Localización: Journal of forensic sciences, ISSN-e 1556-4029, ISSN 0022-1198, Vol. 64, Nº. 3, 2019, págs. 941-945
• Idioma: inglés
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• Resumen

  • Paraquat poisoning usually results from suicide, occupational, or accidental exposure. Herein, we report a rare fatal case of homicidal paraquat poisoning. A 58-year-old man was poisoned by taking paraquat-mixed medicine and wearing paraquat-soaked underwear. In the absence of a history of paraquat exposure, the patient was misdiagnosed with pulmonary infection and scrotal dermatitis and died of respiratory failure 24 days after the initial exposure to paraquat. Ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was applied to detect and quantify paraquat in postmortem specimens. The concentration of paraquat in postmortem specimens from high to low is lung (0.49 ug/g), brain (0.32 ug/g), kidney (0.24 ug/g), liver (0.20ug/g), cardiac blood (0.11ug/mL), and stomach wall (