Resumen de Features and roles of T helper 9 cells and interleukin 9 in immunological diseases
R. Yazdani, Nima Rezaei, S. Shapoori, M. Rezaeepoor, R. Sanaei, M. Ganjalikhani-Hakemi, Gholamreza Azizi, W. Rae, A. Aghamohammadi
T helper 9 (TH9) cells are considered as newly classified helper T cells that have an important role in the regulation of immune responses. Since these cells preferentially produce IL-9, these cells are termed TH9 cells. Recently, the role of TH9 and its signature cytokine (IL-9) has been investigated in a wide range of diseases, including autoimmunity, allergy, infections, cancer and immunodeficiency. Herein, we review the most recent data concerning TH9 cells and IL-9 as well as their roles in disease. These insights suggest that TH9 cells are a future target for therapeutic intervention.
