Ayuda
Ir al contenido

Dialnet


Resumen de EUS-FNA cytological material from pancreatic lesions: the expression of cathepsins and its predictive value of malignancy

Manuela Roger, Juan F. Martínez, Gloria Peiró Cabrera, José Ramón Aparicio Tormo, Francisco Ruiz Gómez, Luis Compañy, Juan Antonio Casellas

  • Aims: To assess the expression of cathepsins in pancreatic samples obtained by endoscopic ultrasonography and fine needle aspiration (EUS-FNA) and to investigate their relationship with the staging of the pancreatic ductal adenocarcinoma (PDAC). Methods: We prospectively included patients with solid pancreatic masses, in which EUS-FNA were performed. Cathepsins B, L, S and H expression was determined in FNA samples. Results: Seventeen FNA were performed. All cytological material was from PDAC. Expression of cathepsins was predominantly low (B 65%, L 23%, S 76%, and H 41%). We found no correlation between the expression levels and the extension of the neoplasm. Conclusion: Expression of cathepsins in the cytological material of PDAC is diverse but still poor to be useful in the pre-operative diagnosis. There is no correlation between the expression levels of cathepsins and the extension of the PDAC


Fundación Dialnet

Dialnet Plus

  • Más información sobre Dialnet Plus