Resumen de Empowering Students To Design and Evaluate Synthesis Procedures: A Sonogashira Coupling Project for Advanced Teaching Lab

Jun-Yang Ong, Shang-Ce Chan, Truong-Giang Hoang

• A Sonogashira experiment was transformed into a problem-based learning platform for third-year undergraduate students. Given a target that could be synthesized in a single step, students worked in groups to investigate which method was the best for large-scale production. Through this practical scenario, students learn to conduct a literature search, select procedures, practice their synthesis skills, and evaluate their results in a real-world context.