Resumen de The Potential for Postrandomization Confounding in Randomized Clinical Trials

JoAnn E. Manson, Chrisandra L. Shufelt, James M. Robins

• In this Viewpoint, JoAnn Manson and colleagues discuss the risk of postrandomization “confounding,” a bias that can be introduced in long-duration trials of sustained interventions, using statin initiation after randomization in Women’s Health Initiative trials as an example.