What Is in Your Wallet? Quantitation of Drugs of Abuse on Paper Currency with a Rapid LC–MS/MS Method

• Patrick D. Parker ^[1] ; Brandon Beers ^[2] ; Matthew J. Vergne ^[2]
  1. [1] North Carolina State University

     North Carolina State University

     Township of Raleigh, Estados Unidos

     
  2. [2] Lipscomb University

     Lipscomb University

     Estados Unidos

     
• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 94, Nº 10, 2017, págs. 1522-1526
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Laboratory experiments were developed to introduce students to the quantitation of drugs of abuse by high performance liquid chromatography-tandem mass spectrometry (LC–MS/MS). Undergraduate students were introduced to internal standard quantitation and the LC–MS/MS method optimization for cocaine. Cocaine extracted from paper currency was analyzed with a simple and rapid LC–MS/MS method. Students in advanced laboratories determined the amount of amphetamine, methamphetamine, and oxycodone on currency in addition to cocaine. The LC–MS/MS method has a short run time (2.5 min) to allow for a high throughput of student samples.