Resumen de Anchored phosphatases modulate glucose homeostasis

Simon A Hinke, Manuel F Navedo, Allison Ulman, Jennifer L Whiting, Patrick J Nygren, Geng Tian, Antonio Javier Jiménez Caliani, Lorene K. Langeberg, Vincenzo Cirulli, Anders Tengholm, Mark L Dell'Acqua, L Fernando Santana, John D. Scott

• AKAP150 knockout- and mutant knock-in alleles reveal an unexpected role of the adaptor in anchoring phosphatase 2B for efficient insulin secretion from pancreatic β-cells and thus glucose homeostasis.