Resumen de A stomatin dimer modulates the activity of acid-sensing ion channels
Janko Brand, Ewan St J Smith, David Schwefel, Liudmila Lapatsina, Kate Poole, Damir Omerbašić, Alexey Kozlenkov, Joachim Behlke, Gary R. Lewin, Oliver Daumke
Stomatins govern membrane trafficking and ion channel activity. The banana-shaped stomatin-domain dimmers oligomerize into a cylindrical structure. A dynamic hydrophobic pocket at the concave side of the dimer mediates repression of acid-sensing ion channel 3 (ASIC3) activity.
