Resumen de Modulation of synaptic function by VAC14, a protein that regulates the phosphoinositides PI(3,5)P2 and PI(5)P

Yanling Zhang, Amber J McCartney, Sergey N Zolov, Cole J Ferguson, Miriam H. Meisler, Michael A. Sutton, Lois S Weisman

• Mice deficient for VAC14, a scaffolding protein required for PIP2 biosynthesis and linked to human neuropathies, show increased postsynaptic function due to altered AMPA receptor trafficking.