Resumen de Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions

Anitha Suram, Jessica Kaplunov, Priyanka L. Patel, Haihe Ruan, Aurora Cerutti, Virginia Boccardi, Marzia Fumagalli, Raffaella Di Micco, Neena Mirani, Resham Lal Gurung, Manoor Prakash Hande, Fabrizio d'Adda di Fagagna, Utz Herbig

• This study offers a novel view on the role of telomere attrition in human tumours, providing evidence for tumour suppressor activity resulting from telomere dysfunction-induced DNA damage responses.