Ayuda
Ir al contenido

Dialnet


Resumen de A DR4: tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAX

Ryan E Henry, Zdenek Andrysik, Ramiro París, Matthew D Galbraith, Joaquín Espinosa Gallego

  • Depending on the context, cells either arrest or undergo apoptosis in response to p53 activation. Key mediators of both pathways are activated irrespective of the fate choice, but apoptotic cells selectively induce the DR4 death receptor pathway, caspase 8-mediated BID cleavage and activation of BAX.


Fundación Dialnet

Dialnet Plus

  • Más información sobre Dialnet Plus