Resumen de Tyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding

Masayoshi Honda, Yosuke Okubo, Jungmin Yoo, Taekjip Ha, Maria Spies

• The DNA recombination mediator and annealing factor RAD52 is a target of c-ABL activated in response to DNA damage. Engineering of recombinant tyrosine-phosphomimetic RAD52 facilitated studying the consequences of this phosphorylation.