Resumen de Global trigger tools for the detection of adverse drug events

Isabel Gómez Valbuena, Mª Jesús Jiménez Cerezo, Daniele Alioto, José Miguel Ferrari Piquero

• Objective: To analyse the usefulness of «Global Trigger Tools (GTT)» to detect adverse drug events.

  Method: An observational study was conducted over two months, in which daily computing downloads of all patients who presented analytical values of creatinine ≥􀂕2.5 mg/dl, blood glucose 􀀟<50 mg/dl or INR >6 were performed. Subsequently,Electronic Health Records (EHR) were reviewed to determine the cause of this alteration. Considered one positive trigger whose appearance could be related to a drug, without other possible cause.

  Results: The review of the EHR showed that 22.9% of creatinine elevations had positive trigger. The trigger of glucose in 20.3% of cases was associated with a higher dose of insulin than necessary. Finally, in the 85.2% of the trigger of INR were positive.

  Conclusion: Based on our results, we can say that the use of the Global Trigger Tool, by experienced reviewers is useful for detecting drug-related adverse events, with properly completed EHR