Global trigger tools for the detection of adverse drug events

• Autores: Isabel Gómez Valbuena, Mª Jesús Jiménez Cerezo, Daniele Alioto, José Miguel Ferrari Piquero
• Localización: European journal of clinical pharmacy: atención farmacéutica, ISSN 2385-409X, Vol. 18, Nº. 1, 2016, pág. 5
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Objective: To analyse the usefulness of «Global Trigger Tools (GTT)» to detect adverse drug events.

    Method: An observational study was conducted over two months, in which daily computing downloads of all patients who presented analytical values of creatinine ≥􀂕2.5 mg/dl, blood glucose 􀀟<50 mg/dl or INR >6 were performed. Subsequently,Electronic Health Records (EHR) were reviewed to determine the cause of this alteration. Considered one positive trigger whose appearance could be related to a drug, without other possible cause.

    Results: The review of the EHR showed that 22.9% of creatinine elevations had positive trigger. The trigger of glucose in 20.3% of cases was associated with a higher dose of insulin than necessary. Finally, in the 85.2% of the trigger of INR were positive.

    Conclusion: Based on our results, we can say that the use of the Global Trigger Tool, by experienced reviewers is useful for detecting drug-related adverse events, with properly completed EHR