Studying Cooperative Ligand Binding in the Undergraduate Biochemistry Laboratory: Oxygen–Hemoglobin Dissociation Revisited

• Megan K. M. Young ^[1] ; Theodore J. Gries ^[1]
  1. [1] Beloit College

     Beloit College

     City of Beloit, Estados Unidos

     
• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 92, Nº 12, 2015, págs. 2173-2175
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • The interaction between oxygen and hemoglobin is a classic example of a cooperative ligand-binding process. This gaseous-ligand binding process may be studied in the undergraduate laboratory with a variable-pressure cuvette apparatus. An updated method is described to assemble a variable-pressure cuvette apparatus composed of inexpensive supplies and equipment commonly found in the chemistry laboratory.