3D Printing of Protein Models in an Undergraduate Laboratory: Leucine Zippers

• Scott C. Meyer ^[1]
  1. [1] Benedictine University

     Benedictine University

     Township of Lisle, Estados Unidos

     
• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 92, Nº 12, 2015, págs. 2120-2125
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • An upper-division undergraduate laboratory experiment is described that explores the structure/function relationship of protein domains, namely leucine zippers, through a molecular graphics computer program and physical models fabricated by 3D printing. By generating solvent accessible surfaces and color-coding hydrophobic, basic, and acidic amino acid residues, students are able to visualize noncovalent interactions that are important in protein folding and protein–protein interactions.