The topics of nature, for example semiochemicals, are motivating topics, which can be used to teach organic chemistry at high school level. The history, classifications, a few important applications of semiochemicals, and an semiochemical that can be synthesized in the laboratory are presented. The laboratory synthesis is carried out through the well-known Fischer esterification reaction, which is easy to implement in a high school laboratory. Computer-based molecular modeling, based on free software, can be used for supporting the characterization of the synthesized molecule. This information can be used as orientation and motivating material for inquiry- and context-based high-school organic chemistry.
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