Resumen de Synthesis and Kinetics of Hydrolysis of 3,5-Dimethyl-N-acetyl-p-benzoquinone Imine:: An Undergraduate Laboratory

Jeanne M. Buccigross, Christa S. Metz, Lori Elliot, Pamela Becker, Angela S. Earley, Jerry W., Michael Novak, Gayl A. Underwood

• The synthesis of the title compound by a three-step procedure is described. The hydrolysis kinetics, which involve two consecutive psuedo-first-order processes, are also described. The synthesis and kinetics experiments described here are proposed for incorporation into undergraduate laboratory courses under a variety of formats. The compound described here is related to a toxic metabolite of the common analgesics acetaminophen and phenacetin.