Synthesis and Kinetics of Hydrolysis of 3,5-Dimethyl-N-acetyl-p-benzoquinone Imine:: An Undergraduate Laboratory

• Jeanne M. Buccigross ^[2] ; Christa Metz ^[2] ; Lori Elliot ^[2] ; Pamela Becker ^[2] ; Angela S. Earley ^[2] ; Jerry W. ^[2] ; Michael Novak ^[1] ; Gayl A. Underwood ^[1]
  1. [1] Miami University

     Miami University

     Township of Oxford, Estados Unidos

     
  2. [2] College of Mount St. Joseph
• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 73, Nº 4 (April), 1996, págs. 364-367
• Idioma: inglés
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• Resumen

  • The synthesis of the title compound by a three-step procedure is described. The hydrolysis kinetics, which involve two consecutive psuedo-first-order processes, are also described. The synthesis and kinetics experiments described here are proposed for incorporation into undergraduate laboratory courses under a variety of formats. The compound described here is related to a toxic metabolite of the common analgesics acetaminophen and phenacetin.