"Greening Up" the Suzuki Reaction.

• Autores: Evangelos Aktoudianakis, Elton Chan, Amanda R. Edward, Isabel Jarosz, Vicki Lee, Leo Mui, Sonya S. Thatipamala, Andrew P. Dicks
• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 85, Nº 4, 2008, págs. 555-557
• Idioma: inglés
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• Resumen

  • This article describes the rapid, green synthesis of a biaryl compound (4-phenylphenol) via a Pd(0)-catalyzed Suzuki cross-coupling reaction in water. Mild reaction conditions and operational simplicity makes this experiment especially amenable to both mid- and upper-level undergraduates. The methodology exposes students to purely aqueous microscale organic reactivity and showcases topical research in the milieu of an industrially applicable process.