Commelina benghalensis es una planta herbácea que para la medicina tradicional posee propiedades antimicrobianas, anti-inflamatorias y abortifacientes. No obstante, no se tienen informes en la literatura de evaluaciones sobre el efecto antimicrobiano de sus extractos. Se evaluaron extractos de etanol y agua de la planta total, fresca y secada a la sombra. Los extractos de la planta seca aportaron los rendimientos de 4,35% para el alcohol y 5,53% para el agua y la planta fresca 1,20% para el alcohol y 1,24 para el agua. El tamizaje fitoquímico demuestra la posible presencia de 10 grupos diferentes de productos naturales para los extractos de alcohol y 5 para los de agua. Los extractos de alcohol por lo tanto tienen más posibilidades de poseer actividad biológica de interés. Los extractos de alcohol son mas activos como antimicrobianos siendo el orden de actividad Candida albicans > Escherichia coli > Staphylococcus aureus.La actividad es comparable a gentamycina y nystatin utilizados como controles positivos. Los extractos acuosos no mostraron actividad frente a los tres microorganismos evaluados.
Commelina benghalensis has been reported in folkloric medicine to poses antimicrobial, anti-inflammatory and abortifacient properties. However, neither phytochemical nor antimicrobial evaluation of this plant has been reported in literature. The extracts from shade dried plant material yielded greater percentages of extractives from the same amount of plant material than the extracts from freshly collected plant material. Dry plant material produces 4,35% for ethanol extract and 5.53% for aqueous extract > that from the fresh plant material; 1,20% for ethanol extract and 1,24% for aqueous extract. The phytochemical screen led to the discovery that Commelina benghalensis contains 10 pharmacologically active chemical compounds and all these were present in the ethanol extracts while only 5 of these were present in the aqueous extracts thus rendering the ethanol extracts more pharmacologically active than the aqueous extracts. The ethanol extracts are superior in performance to the aqueous extracts. In both ethanolic extracts, activity against Candida albicans > Escherichia coli > Staphylococcus aureus. The ethanol extracts showed relatively comparable activities to gentamycin and nystatin which are locally available standard antimicrobial agents on the market. Aqueous extracts showed virtually no activity against the Staphylococcus aureus, Escherichia coli and Candida albicans strains.
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