Clinical & translational oncology

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  Año 2026, Vol. 28, Número 5

  • EDITORIAL

    • Do glucocorticoids affect the efficacy of immune checkpoint inhibitors?

      Yefei Shu

      págs. 1461-1463

      

  • REVIEW ARTICLE

    • CTC cluster in breast cancer: synergetic metastasis promotion mechanism and transformation path from platelet cloaking to leukocyte escort

      Cangtai Guan, Liangyu Hao, Biyao Gong, Lixiang Zheng

      • Resumen

      págs. 1464-1475

      

    • Role of surgery in metastatic gastric cancer

      Israel Manzanedo Romero, Ángel Serrano del Moral, Estibaliz Perez Viejo, Fernando Pereira Pérez

      • Resumen

      págs. 1476-1483

      

    • Targeting prostate adenocarcinoma tumor microenvironment via cancer nanotheranostics: a comprehensive update on improved roadmap for disease diagnosis, therapy and management

      Abdul Wasai, Adhiraj Roy, Deepti Pandita

      • Resumen

      págs. 1484-1500

      

    • Emerging therapeutic strategies for CD30-positive lymphomas

      Alberto Boretti

      • Resumen

      págs. 1501-1515

      

    • Redefining oropharyngeal cancer in the HPV era: integrating precision medicine and immunotherapeutic frontiers

      Seyed Ebrahim Alavi, Lavanya Ajay Sharma, Ajay Sharma, Hasan Ebrahimi Shahmabadi

      • Resumen

      págs. 1516-1548

      

    • Overcoming tumour resistance in cancer immunotherapy through predictive and pharmacodynamic biomarkers

      Heena Kansal, Vishal Chopra, Kranti Garg, Siddharth Sharma

      • Resumen

      págs. 1549-1569

      

    • Biological multi-omics approaches to next-generation biomarkers in immune-related disorders and malignancies: An overview

      Pawan Kumar Goswami, Sandip Chatterjee

      • Resumen

      págs. 1570-1585

      

    • A comprehensive review of sex differences in the clinical outcomes to immunotherapy on solid tumors

      Juan Carlos Redondo González, Luis Posado Domínguez, Laura Corvo Félix, Lorena Bellido, Iñigo San Miguel Arregui, Emilio Fonseca Sánchez, Alejandro Olivares Hernández, Edel del Barco Morillo

      • Resumen

      págs. 1586-1594

      

  • CLINICAL GUIDES IN ONCOLOGY

    • SEOM–GEMCAD–TTD clinical guideline for the diagnosis and treatment of esophageal cancer (update 2025)

      Ana Fernández Montes, Julia Alcaide García, Ana Custodio, Lourdes Fernández Franco, Javier Gallego Plazas, Carlos Gómez Martín, Paula Richart Aznar, Fernando Rivera Herrero, María Alsina Maqueda

      • Resumen

      págs. 1595-1609

      

    • SEOM-GECOD clinical guideline for cancer of unknown primary (update 2025)

      Fernando Losa Gaspà, Olatz Etxaniz Ulazia, Alejandra Giménez Ortiz, Paula Gomila, Lara Iglesias Docampo, Federico Longo Muñoz, Esteban Nogales, Antonio Sánchez, Gema Soler González, Isaura Fernández Pérez

      • Resumen

      págs. 1610-1623

      

  • RESEARCH ARTICLE

    • Is the risk of brain metastasis and prognosis different in HER2-low breast cancer?

      Yaşar Culha, Beyza Ünlü, Sena Ece Davarcı, Halil Göksel Güzel, Hacer Demir, Banu Öztürk, Meltem Baykara

      • Resumen

      págs. 1624-1636

      

    • Anxiety in breast cancer research (1982–2024): a bibliometric analysis

      Jie Hou, Yaqin Meng, Lei Zhang, Haixia Fan, Minheng Zhang

      • Resumen

      págs. 1637-1651

      

    • The Oncotype DX® 21-gene recurrence score and clinical outcomes in hormone receptor-positive, HER2-negative male breast cancer: a scoping review

      Silvia Mezi, Giulia Pomati, Antonella Chiavassa, Valentina Silvestri, Laura Ottini

      • Resumen

      págs. 1652-1661

      

    • Associations between molecular subtypes and high-risk pathological factors in endometrial cancer

      Xueqing Sun, Jing Xue, Zhen Sun, Wei Tian, Xiao Song, Ran Chu, Ming Liu

      • Resumen

      págs. 1662-1672

      

    • Clinical and molecular determinants of response to maintenance olaparib for primary and recurrent epithelial ovarian carcinoma

      Matthew K. Wagar, Kharmen Bharucha, Lauren Montemorano, Laura B. Huffman, Amy L. Godecker, Lisa M. Barroilhet

      • Resumen

      págs. 1673-1682

      

    • Needs and opportunities for improvement in the management and monitoring of gynaecological cancer in Spain

      Ainhoa Madariaga Urrutia, Marisa Cots, Charo Hierro, Carlos Robles, Sonia Garrido, Pilar Barretina Ginesta, Ariadna Serrano, Marta Serena, Patricia Salcedo, Noelia Mariátegui, Eva María Guerra Alía

      • Resumen

      págs. 1683-1690

      

    • Exploring the prognostic value of the magnesium–immune prognostic score (MIPS) in metastatic non-small cell lung cancer receiving Nivolumab

      Sait Kitapli, Melih Akpunar, Ali Alkan, Ozgur Tanriverdi

      • Resumen

      págs. 1691-1707

      

    • Machine learning models for predicting response to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer brain metastases: a systematic review and meta-analysis

      Bardia Hajikarimloo, Ibrahim Mohammadzadeh, Rana Hashemi, Salem Mohammed Tos, Ehsan Bahrami, Dorsa Najari, Azin Ebrahimi, Arman Hasanzade, Mohammad Amin Habibi

      • Resumen

      págs. 1708-1717

      

    • Neuroactive ligand–receptor interaction in gastric cancer: a comprehensive spatial single-cell analysis

      Lirong Chen, Xiao Li, Shaocong Mo, Shenyang Zhao, Jiayue Zheng, Kexin Cheng, Yi Zhang, Feifei Luo, Wanwei Zheng

      • Resumen

      págs. 1718-1731

      

    • Gastric cancer burden and regional disparities among Helicobacter pylori–positive patients in the Americas: a systematic review and meta-analysis

      Francisco Cezar Aquino de Moraes, Luis Eduardo Rodrigues Sobreira, Nuris Maria Torres Argota, Emanuele Rocha da Silva, Gustavo Tadeu Freitas Uchôa Matheus, Rommel Mario Rodríguez Burbano

      • Resumen

      págs. 1732-1746

      

    • Global trends in artificial intelligence applications for gastric cancer prediction, treatment, and management: a topic modeling and bibliometric analysis

      Vu Anh Trong Dam, Jeongseon Kim

      • Resumen

      págs. 1747-1760

      

    • Development and validation of a cuproptosis-related gene signature for predicting prognosis and drug sensitivity in gastric cancer

      Hongxin Huang, Funing Zhang, Zetian Chen, Jihuan Wang, Yifan Zou, Weizhi Wang, Zekuan Xu

      • Resumen

      págs. 1761-1778

      

    • Development and validation of a personalized web-based calculator of aggressive recurrence after surgery for early-stage hepatocellular carcinoma by machine learning

      Zi Chen Yu, Kai Wang, Wen Feng Lu, Zheng Kang Fang, Kai Di Wang, Zi Yang Bao, Zhe Jin Shi, Jun Wei Liu, Dong Sheng Huang, Cheng Wu Zhang, Lei Liang, Yang Yu

      • Resumen

      págs. 1779-1791

      

    • Prognostic value of PLN, LNR, and LODDS in advanced colorectal signet ring cell carcinoma

      Liang Chu, Cenzhu Wang, Han Wang, Yucheng Ding, Shuhan Feng, Yan Zhang, Yanan Zheng, Fuchao Li, Lei Liu

      • Resumen

      págs. 1792-1806

      

    • Response rate and long-term survival in patients with advanced melanoma: data from the prospective cohort study gem-1801

      E. Espinosa Arranz, Miguel Ángel Berciano Guerrero, Eva Muñoz Couselo, Teresa Puértolas Hernández, José Luis Manzano Mozo, Ainara Soria, Pablo Ayala de Miguel, Guillermo Crespo, Lourdes Gutiérrez Sanz, Pablo Cerezuela Fuentes, Carlos Aguado de la Rosa, Margarita Majem, Almudena García Castaño, Alfonso Berrocal Jaime, Francisco Ramón García Arroyo, María Rodríguez de la Borbolla, Lorena Bellido, Javier Medina Martínez, Luis Antonio Fernández Morales, Alfonso Martín Carnicero, R. Lopez Castro, Aida Bujosa Rodríguez, María José Lecumberri Biurrun, José Carlos Villa Guzmán, Iván Márquez Rodas

      • Resumen

      págs. 1807-1814

      

    • Evaluation of GPA, molGPA and prognostic factors in melanoma brain metastases: a single-center study

      Jens Christian Philippi, Niklas Mittenbacher, Dirk Vordermark, Daniel Medenwald, Jörg Andreas Müller

      • Resumen

      págs. 1815-1824

      

    • A radiogenomics biomarker based on tumor angiogenesis for non-invasive prognosis of clear cell renal cell carcinoma

      Yuanchao Li, Youting Huang, Haiyun Xu, Shuohui Yang

      • Resumen

      págs. 1825-1838

      

    • Clinical and treatment patterns of advanced and radioiodine-refractory differentiated thyroid cancer. ERUDIT study

      Carlos López López, Marcel Sambo Salas, Lorenzo Orcajo Rincón, Manuel Durán Poveda, Julio R. Villanueva, Rita Joana Santos, Marta Llanos Muñoz, Elena Navarro González, Javier Aller Pardo, Virginia Pubul Núñez, Sonsoles Guadalix Iglesias, Guillermo Crespo, Cintia González, Carles Zafón Llopis, Miguel Navarro, Francisco Javier Santamaría Sandi, Angel Agustín Segura Huerta, Pablo Gajate Borau, Marcelino Gómez Balaguer, Javier Valdivia Bautista, Jordi L. Reverter Calatayud, Juan Carlos Galofré Ferrater, Beatriz Castelo Fernández, María José Villanueva, Juan Antonio Vallejo Casas

      • Resumen

      págs. 1839-1852

      

    • Investigating the predictive role of inflammatory indices in cancer metastasis

      Mohammad Reza Moghaddasnejad, Tina Vosoughi, Negar Sadat Sherafat, Saeid Bitaraf, Najmaldin Saki

      • Resumen

      págs. 1853-1860