Electrical Characterization of Biological Elements by Atomic Force Microscopy

• Autores: Ignacio Casuso Páramo
• Directores de la Tesis: Gabriel Gomila Lluch (dir. tes.)
• Lectura: En la Universitat de Barcelona ( España ) en 2008
• Idioma: inglés
• Tribunal Calificador de la Tesis: Josep Samitier Martí (presid.), Esteve Padrós i Morell (secret.), Julio Gómez Herrero (voc.), Marco Sampietro (voc.), Juan José Sáenz Gutiérrez (voc.)
• Materias:
  • Física
    • Electrónica
      • Transporte de electrones
  • Ciencias de la vida
    • Biofísica
      • Bioenergética
• Enlaces
  • Tesis en acceso abierto en:  TDX  Dipòsit Digital de la UB 
• Resumen

  • The assessment of the electrical properties of biomolecules at the nanoscale becomes necessary for gathering previous basic knowledge and for the control of the biosensor fabrication. I developed instrumentation, protocols, and theoretical frameworks for the nanoscale electrical characterization of biomolecules by AFM. Two novel types of AFM electrical characterizations were developed: electron transport through the biomolecules and dielectric polarization of the biomolecules (each one requires different instrumentation, protocols and theory). I succeeded in obtaining important electrical information on individual biomolecules with implications in electrical biosensor fabrication.KEY WORDS: AFM, Protein, Electrical, Biosensor