A computational study of transport phenomena in haemodynamics: biodegradable stents and thrombus formation in the left atrial appendage

• Autores: Jorge Dueñas Pamplona
• Directores de la Tesis: Javier García García (dir. tes.), José Benito Sierra Pallares (codir. tes.)
• Lectura: En la Universidad Politécnica de Madrid ( España ) en 2022
• Idioma: inglés
• Tribunal Calificador de la Tesis: José María Goicolea Ruigómez (presid.), Conrado Ferrera Llera (secret.), Juan Carlos del Álamo de Pedro (voc.), Jesús Carlos Martínez Bazán (voc.), Francisco Castro Ruiz (voc.)
• Programa de doctorado: Programa de Doctorado en Energía Sostenible Nuclear y Renovable por la Universidad Politécnica de Madrid
• Menciones:
  • Internacional
• Calificación: Sobresaliente Cum Laude
• Materias:
  • Física
    • Física de fluidos
      • Mecánica de fluidos
  • Ciencias médicas
    • Patología
      • Patología cardiovascular
• Enlaces
  • Tesis en acceso abierto en: Archivo Digital UPM
• Resumen

  • Cardiovascular diseases are the leading cause of mortality worldwide. In recent years, the usefulness of computational fluid mechanics for the study of these diseases has been demonstrated. If these simulations are also supported by new imaging techniques, they allow us to advance in the treatment and prevention of these diseases, since they allow for a personalized study of the patient. These ad hoc studies are considered to be one of the challenges with the greatest potential impact on cardiovascular biomechanics. The work developed throughout this PhD thesis will focus mainly on the study of blood flow in two areas: in coronary arteries with biodegradable stents and in the left atrial appendage (cavity located in the left atrium of the heart). It is therefore a study of flow at reduced scales and with complex boundary conditions. Therefore, although the specific objectives are different, many of the techniques that will be used for theoretical, experimental, and numerical modelling will be similar. The common objective is to apply the tools of experimental and numerical fluid mechanics to the personalized study of patients in order to obtain criteria and guidelines for action that can be useful in clinical practice.