Ehunen ingeniaritzarako tinta eta 3D bidez inprimatutako aldamio biomimetikoen garapena
- Autores: Teresa Carranza Fernandino
- Directores de la Tesis: Koro de la Caba Ciriza (dir. tes.), Pedro Guerrero (codir. tes.)
- Lectura: En la Universidad del País Vasco - Euskal Herriko Unibertsitatea ( España ) en 2025
- Idioma: euskera
- Programa de doctorado: Programa de Doctorado en Ingeniería de Materiales Renovables por la Universidad del País Vasco/Euskal Herriko Unibertsitatea
- Materias:
- Enlaces
- Tesis en acceso abierto en: ADDI
- Resumen
The development of printable materials is a rapidly expanding area, as manufacturing technologies have become increasingly popular and accessible. These technologies have found applications across various fields, including industrial, educational, dental, and biomedical sectors. In particular, biomimetic-engineered 3D printed parts have shown promising results. However, there is still a significant need for further research and development to use natural source materials for this purpose. In this context, the overall objective of this thesis was to develop 3D printable inks using natural materials to obtain structures capable of physicochemically and mechanically mimicking human tissues. Moreover, the study of the suitability of different characterization methods and the study of these characterization techniques to consolidate standardized techniques for each material is a secondary objective. In particular, protein-polysaccharide inks have been successfully developed and the effect of the sterilization methods and the addition of other biopolymers and antioxidant had in the 3D printing process and in the properties of the resulting scaffolds was analyzed. Furthermore, the combination of 3D printing and electrospinning with the aim of developing scaffolds with a hierarchical porous structure to promote cell adhesion and proliferation was assessed. Finally, different strategies to crosslink gelatin-based scaffolds were studied to enhance the mechanical performance of the scaffolds.
