The field of Rare Event Searches can count on a great ally: the Time Projection Chamber (TPC). Despite all the technological advancements which already occurred, TPCs still have to adapt to more and more stringent requirements, as the experiments need more and more sensitivity. This implies a continuous R and D effort, which has driven this work, too. In particular, this thesis proposes some practical solutions to common problems encountered in TPCs: the development of tunable resistive materials capable of spark protection in cryogenic conditions, a local dual-phase concept (bubble- assisted LHMs), the study of secondary scintillation of Ar/CF4 mixtures, relevant, among others, for high pressure TPCs, and easily scalable, thick structures for electroluminescence with competitive light yields and energy resolutions.
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