The immune response of the mussel mytilus galloprovincialis. Transcriptomics, proteomics and evolutionary aspects

• Autores: Amaro Saco Beiroa
• Directores de la Tesis: Antonio Figueras Huerta (dir. tes.), Beatriz Novoa Garcia (dir. tes.)
• Lectura: En la Universidade de Vigo ( España ) en 2024
• Idioma: español
• Tribunal Calificador de la Tesis: Cristián Gallardo-Escárate (presid.), Paloma Morán Martínez (secret.), Carmen Bouza Fernández (voc.)
• Programa de doctorado: Programa de Doctorado en Metodología y Aplicaciones en Ciencias de la Vida por la Universidad de Vigo
• Materias:
  • Ciencias de la vida
    • Biología animal (zoología)
      • Genética animal
    • Inmunología
• Enlaces
  • Tesis en acceso abierto en: Investigo
• Resumen

  • My PhD Thesis was focused on the study of genetic variability in the immune system of the mussel Mytilus galloprovincialis. I studied the immune response of this species to marine pathogens by performing transcriptomic and proteomic analyses. Some of the main immune gene families that were leading the response in these studies were further analysed through comparative genomics with an evolutionary approach. I revealed large gene family expansions characterizing the immune system of mussel, studied the conservation of such expansions in other bivalves with respect to other metazoans and related it to functional diversifiaction using expression data.