Development of a simulation platform for the evaluation of PET neuroimaging protocols in epilepsy

• Autores: José Paredes Pacheco
• Directores de la Tesis: Pablo Aguiar Fernández (dir. tes.), Nuria Roe Vellve (dir. tes.)
• Lectura: En la Universidade de Santiago de Compostela ( España ) en 2022
• Idioma: inglés
• Número de páginas: 180
• Tribunal Calificador de la Tesis: Xavier Setoain Perego (presid.), Julia Cortés Hernández (secret.), Alexis Moscoso Rial (voc.)
• Programa de doctorado: Programa de Doctorado en Neurociencia y Psicología Clínica por la Universidad de A Coruña; la Universidad de Santiago de Compostela y la Universidad de Vigo
• Materias:
  • Ciencias médicas
    • Ciencias clínicas
  • Ciencias tecnológicas
    • Tecnología de los ordenadores
• Enlaces
  • Tesis en acceso abierto en: MINERVA
• Resumen

  • Monte Carlo simulation of PET studies is a reference tool for the evaluation and standardization of PET protocols. However, current Monte Carlo software codes require a high degree of knowledge in physics, mathematics and programming languages, in addition to a high cost of time and computational resources. These drawbacks make their use difficult for a large part of the scientific community. In order to overcome these limitations, a free and an efficient web-based platform was designed, implemented and validated for the simulation of realistic brain PET studies, and specifically employed for the generation of a wellvalidated large database of brain FDG-PET studies of patients with refractory epilepsy.