Implications of PD-L1 Expression in Oral Squamous Cell Carcinomas

• Autores: Lenouvel Daniel
• Directores de la Tesis: Miguel Ángel González Moles (dir. tes.), Pablo Ramos-García (dir. tes.)
• Lectura: En la Universidad de Granada ( España ) en 2021
• Idioma: inglés
• Número de páginas: 75
• Enlaces
  • Tesis en acceso abierto en: DIGIBUG
• Resumen

  • In summary, this thesis adds to the understanding of PD-L1 expression in OSCC. Specifically, that PD-L1 expression is increased in non-smokers, non-drinkers and potentially in women as well. That PD-L1 expression is increased in tumours with an intense inflammatory infiltrate. That PD-L1 expression is increased in the epithelium adjacent to the tumour and this may play a role in oncogenesis. Finally, we have shown evidence that the presence of PD-L1 expression in the tumour cell membrane may predict a worse likelihood of survival.