Introducción: En la actualidad, no se han descrito criterios claros de curación de la osteomielitis de Pie Diabético, que permitirían definir indicadores de evolución y resolución basados en marcadores analíticos y radiológicos.
Objetivo: Identificar la capacidad predictiva de los distintos parámetros analíticos y radiológicos ante la aparición de un evento de complicación.
Metodología: Estudio observacional prospectivo, en el que se han analizado parámetros analíticos y signos radiológicos en 116 pacientes con osteomielitis de Pie Diabético, tras la cicatrización de la úlcera y durante un período de seguimiento de 12 meses.
Resultados: Valores elevados de linfocitos y albúmina son factores predictores en la aparición de evento de complicación en el seguimiento a 12 meses una vez ha cicatrizado la úlcera. La elevación de la velocidad de sedimentación globular y la no curación radiológica han supuesto factores predictores y diagnósticos ante un evento de complicación y por otro lado, la elevación de la proteína C reactiva y la glucemia han sido factores diagnósticos ya que su elevación se produce durante la aparición del evento.
Discusión: Es necesario incluir modelos de seguimiento a largo plazo en pacientes cicatrizados tras un proceso de osteomielitis de Pie Diabético, mediante la realización de analíticas sanguíneas y radiografías seriadas. Las recomendaciones actuales en pacientes en periodo de remisión de la osteomielitis provocan una detección tardía de las complicaciones que pueden surgir a largo plazo.
Conclusiones: En el periodo de remisión de los pacientes con osteomielitis de Pie Diabético, los parámetros analíticos asociados a la aparición de complicaciones durante el seguimiento son, la elevación de los valores de linfocitos, velocidad de sedimentación globular, proteína C reactiva, albúmina y glucemia. La no curación radiológica en el periodo de remisión de la osteomielitis de Pie Diabético, es un factor de riesgo de desarrollo de complicaciones.
¿ Introduction: Currently, there is a need to identify and formulate clear criteria for the cure of diabetic foot osteomyelitis. This will permit in turn to establish evolution and resolution indicators based on analytical and radiological markers.
Aim: To identify the predictive capacity of different analytical and radiological parameters in the onset of a complication event.
Methods: We conducted a prospective observational study with 116 patients diagnosed with diabetic foot osteomyelitis. Blood tests and radiographs were analysed after ulcer healing in a follow-up of 12 months.
Results: Regarding parameters affecting a complication event, we observed that elevated values of lymphocytes and albumin are predictive factors at 12-month follow-up once the ulcer has healed. The elevation of erythrocyte sedimentation rate and the absence of cure according to radiology had predictive and diagnostic value in the onset of a complication event. In contrast, the elevation of C-reactive protein and blood glucose were diagnostic factors since their elevation occurs during the onset of the event.
Discussion: It is necessary to include long-term follow-up models in patients with diabetic foot osteomyelitis after ulcer healing, using blood tests and serial radiographs. Current recommendations in patients in remission period of osteomyelitis could cause a delay in the detection of complications that may arise during long-term.
Conclusions: In the remission period of the patients with diabetic foot osteomyelitis, the analytical parameters associated with the onset of complications during the follow-up are: elevation of lymphocyte values, erythrocyte sedimentation rate, C-reactive protein, albumin and blood glucose. Absence of cure according to radiology is a risk factor for the development of complications during the period of remission of diabetic foot osteomyelitis.
¿ Introduction: Currently, there is a need to identify and formulate clear criteria for the cure of diabetic foot osteomyelitis. This will permit in turn to establish evolution and resolution indicators based on analytical and radiological markers.
Aim: To identify the predictive capacity of different analytical and radiological parameters in the onset of a complication event.
Methods: We conducted a prospective observational study with 116 patients diagnosed with diabetic foot osteomyelitis. Blood tests and radiographs were analysed after ulcer healing in a follow-up of 12 months.
Results: Regarding parameters affecting a complication event, we observed that elevated values of lymphocytes and albumin are predictive factors at 12-month follow-up once the ulcer has healed. The elevation of erythrocyte sedimentation rate and the absence of cure according to radiology had predictive and diagnostic value in the onset of a complication event. In contrast, the elevation of C-reactive protein and blood glucose were diagnostic factors since their elevation occurs during the onset of the event.
Discussion: It is necessary to include long-term follow-up models in patients with diabetic foot osteomyelitis after ulcer healing, using blood tests and serial radiographs. Current recommendations in patients in remission period of osteomyelitis could cause a delay in the detection of complications that may arise during long-term.
Conclusions: In the remission period of the patients with diabetic foot osteomyelitis, the analytical parameters associated with the onset of complications during the follow-up are: elevation of lymphocyte values, erythrocyte sedimentation rate, C-reactive protein, albumin and blood glucose. Absence of cure according to radiology is a risk factor for the development of complications during the period of remission of diabetic foot osteomyelitis.
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