Estudio epidemiológico y caracterización genética del virus de la hepatitis e en explotaciones porcinas
- Autores: Salceda Fernández-Barredo y del Amo
- Directores de la Tesis: María Teresa Pérez Gracia (dir. tes.), Ángel García Muñoz (codir. tes.)
- Lectura: En la Universidad CEU - Cardenal Herrera ( España ) en 2007
- Idioma: español
- Tribunal Calificador de la Tesis: José Manuel Sánchez-Vizcaíno Rodríguez (presid.), María Teresa Gómez Muñoz (secret.), Manuel Antonio Rodríguez Iglesias (voc.), Maria Esperanza Gómez Lucía-Duato (voc.), Malcolm Banks (voc.)
- Materias:
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- Resumen
This study describes the distribution of Hepatitis E virus (HEV) in a naturally infected swine population and the genetic relatedness of HEV strains on swine farms in Spain. Of fecal and serum samples collected from 191 pigs and manure-ditch samples collected from 21 farms, HEV was detected in 19%, 12%, and 38%, respectively, for an overall prevalence rate of 25%. The maximum prevalence rates for feces and serum were in pigs 13 to 16 wk old. A high prevalence of the virus in feces (18%) was observed in sows. Gene sequencing was performed on 30 strains from feces, serum, and manure ditch: the nucleotide identities varied from 85% to 99% when compared with those of other strains of genotype 3 isolated from swine. This is the first study in Europe to show the variation in virus distribution by age in feces and serum in a naturally infected swine population.
